Hayley Klein, MD | Pediatric Ophthalmologist and eye care specialist in Fort Mill, SC and Rock Hills, SC
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Fort Mill

Fellowship Trained

Pediatric Eye Care

Clinical Interests

Eye Exams & Routine Eye CareStrabismusPediatric Eye Care

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Dr. Hayley Klein is a pediatric ophthalmologist who specializes in adult and childhood strabismus. She earned her bachelor's degree from the University of Houston and her medical degree from Baylor College of Medicine. Her internship was in the Michael E. DeBakey Department of Surgery at Baylor College of Medicine. Dr. Klein's ophthalmology residency was at the Saint Louis University Department of Ophthalmology and her pediatric ophthalmology fellowship was with University Hospitals Rainbows Babies and Children's Hospital.

Prior to joining CEENTA, Dr. Klein was an assistant professor in the Center for Pediatric Ophthalmology and Adult Strabismus at Rainbow Babies and Children's Hospital and University Hospitals Eye Institute.

*To view Dr. Kleins media appearances, click on the three lines near the top right of the YouTube player.

As a pediatric eye doctor, Dr. Klein sees children with any eye concerns from infancy through 18 years old. She also sees adults with strabismus, or misalignment of the eyes. Some of the most common conditions she sees are:

Failed vision screens: Children may fail vision screenings performed by pediatricians or schools for any number of reasons. If your child fails a vision screen, it is of the utmost importance to see an eye care professional to make sure there are no vision-threatening concerns.

Glasses Exams for Children: Glasses exams for adults are not the same as glasses exams for children. They require special training, medications, and techniques to ensure young children receive a proper glasses prescription.

Amblyopia: Amblyopia is poor vision in one eye that occurs when the brain doesn't learn how to see from the eye. It can happen for many reasons and must be caught and treated from an early age in order to cure it.

Strabismus (Childhood and Adult): Strabismus refers to any misalignment of the eyes (crossing inwards, drifting outwards, or other patterns). It most commonly affects children, but can persist into adulthood as well. Strabismus can be treated at any age.

Nasolacrimal Duct Obstruction: Nasolacrimal duct obstruction is a condition that affects infants. The tear drainage system doesn't form properly, so the infant's tears roll down their cheeks instead of going through the normal drainage system.

Retinopathy of Prematurity: Infants who are born extremely premature (less than 30 weeks gestation) or extremely small (less than 3.3 pounds) are at high risk for Retinopathy of Prematurity (ROP). These infants must have routine eye screening exams to ensure that they do not loose vision permanently from this disease. Dr. Klein performs these exams while in-patient, and continues the exams as out-patients for those who need it.

Developmental Delays and Autism Diagnostics: Any time there are behavioral concerns or developmental delays, it's a good idea to have a comprehensive eye exam by a trained eye care specialist. We want to make sure that there are no eye concerns contributing to the problem. Furthermore, if your child has behavioral concerns or developmental delays, they may not be able to voice their eye complaints in the usual way.

Dr. Klein practices in our Fort Mill (601 S. Sutton Road, Suite 201, Fort Mill, SC) office. To make a pediatric eye care appointment with her, you may do so online or through myCEENTAchart.

Education & Fellowship

Bachelor of Science in Anthropology, Biology Minor, University of Houston, 2008
Summa Cum Laude with University Honors and Honors in Major

Doctor of Medicine, Baylor College of Medicine, 2014

General Surgery Preliminary Year, Michael E. DeBakey Department of Surgery at Baylor College of Medicine, 2015

Saint Louis University Department of Ophthalmology, 2018

Pediatric Ophthalmology, University Hospitals Rainbow Babies and Children's Hospital, 2019

Associations & Memberships

American Board of Ophthalmology, 2018-present

American Association for Pediatric Ophthalmology and Strabismus, 2018-present


My daughter Elise had a blocked tear duct, and Dr. Hayley Klein was wonderful with the repair.     - Jessica N.
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Dr. Hayley Klein and her staff at CEENTA were absolutely wonderful.     - Ritta R.
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Diagnosis and Management of Acute Closed Angle Glaucoma after Autologous Hematopoietic Stem Cell Transplant. Holmes, T.L.; Chopra, H.K.; Dababneh, D.; Thomas, F.P.; Rajeh, N.; Lionberger, J.M.

  • Collaboration with Hematology and Oncology Department at Saint Louis University
  • Abstract accepted at American Society of Blood and Marrow Transplant meeting 2016
  • Poster presented at 2016 SLU Resident Poster Competition


Hamill EB, Wang L,Chopra HK, Hill W, Koch DD. Intraocular lens power calculations in eyes with previous hyperopic laser in situ keratomileusis or photorefractive keratectomy. J Cataract Refract Surg. 2017;43(2):189-194.

Giagtzoglou N, Yamamoto S, Zitserman D, Graves HK, Schulze KL, Wang H, Klein H, Roegiers F, Bellen HJ. dEHBP1 controls exocytosis and recycling of Delta during asymmetric divisions. J Cell Biol. 2012;196(1):65-83.

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