Dr. K. Casey Mathys is a fellowship-trained cornea specialist who specializes in the cornea, external diseases, LASIK, and refractive eye surgery. Dr. Mathys received his Bachelor of Science degree in neuroscience and behavioral biology from Emory University and his medical degree from Case Western Reserve University School of Medicine. His internship was at the University of California at San Diego. His ophthalmology residency was at the University of North Carolina at Chapel Hill, where he also served as chief resident from 2007-08. His fellowship in cornea, external diseases, and refractive surgery was from Eye Consultants of Atlanta at Piedmont Hospital. Dr. Mathys has been published in numerous medical journals, written book chapters on cornea disease, and has lectured at a number of national meetings. He is board-certified by the American Board of Ophthalmology and is a member of the American Academy of Ophthalmology.
Dr. Mathys has also served on three foreign mission eye surgery trips. He traveled to Honduras twice, performing cataract surgery on those in need of care. He has also traveled to Vietnam, where he helped to train their corneal surgeons on techniques of corneal transplantation.
In his free time, Dr. Mathys enjoys spending time with his family, volunteers as a Cub Scout Den Leader, and is very active outdoors.
Dr. Mathys practices in our SouthPark (6035 Fairview Road, Charlotte, NC) and Belmont (400 Park Street, Belmont, NC) offices. To make an appointment with him, call 704-295-3000. You can also request an appointment online or through myCEENTAchart.
Education & Fellowship
B.S. in Neuroscience and Behavioral Biology, Emory University, 1999
Case Western Reserve University School of Medicine, 2004
University of California, San Diego, 2005
University of North Carolina at Chapel Hill, University of North Carolina Hospitals, 2008
Chief resident, 2007-08
Cornea, External Disease, and Refractive Surgery, Eye Consultants of Atlanta, 2009
Associations & Memberships
- American Board of Ophthalmology
- American Academy of Ophthalmology, Fellow
- American Society of Cataract and Refractive Surgery
Refractive cataract surgery with Tecnis Multifocal lens and Symfony and Symfony toric extended depth of focus lenses.
Femto Laser-Assisted Cataract Surgery, or FLACS, replaces many of the steps during cataract surgery that require a blade and softens the cataract, allowing for an easier and smoother removal. In addition, the laser corrects mild astigmatism by relaxing the cornea at a precise depth, length, and orientation in a more precise and effective manner compared to manual, hand-made incisions. It can also improve the quality of vision by reducing some visual aberrations, it expands the visual range of astigmatism-correcting lens implants, and it may enhance the quality and range of near vision in extended range lens implants.
Corneal Crosslinking for non-invasive treatment of moderate keratoconus
Cornea Transplantation and Ultrathin, partial thickness corneal transplantation (DSAEK and DMEK)
BlephEx is an in-office procedure for removing excess bacteria and cleaning eyelid margins. The treatment takes only a few minutes to perform and can eliminate chronic and irritating symptoms associated with dry eye and blepharitis.
Business North Carolina Top Doctors, 2020
SouthPark Magazine Top Doctors, 2020
Charlotte Magazine Top Doctors, 2020
Frederick W Stocker Resident Research Award, University of North Carolina, Department of Ophthalmology, 2008
Resident of the Year, University of North Carolina, Department of Ophthalmology , 2006-07
Frederick W Stocker Resident Research Award, University of North Carolina, Department of Ophthalmology, 2007
Research to Prevent Blindness, clinical research grant, 2006
Diabetes Association of Greater Cleveland, Summer Research Fellowship, 2001
Cataract Surgical Mission to San Pedro Sula, Honduras, Project E.C.H.O., Sept 2013
Cataract Surgical Mission to San Pedro Sula, Honduras, Project E.C.H.O., Feb 2009
Corneal Surgical Mission to Hanoi, Vietnam, ORBIS, April 2007
Dr. Mathys has given continuing education talks including:
"The evolution of endothelial keratoplasty, DSEK to DMEK”
"Herpetic Eye Disease - Don't Forget About It!"
I have had ocular rosacea for over two years. I came to see Dr. Mathys
, and not only did he also diagnose me with blepharitis, but he also recommended treatment with BlephEx. - Laura C.
Mathys KC, Lee WB. Vernal Keratoconjunctivitis. In: Holland EJ, Mannis MJ, Lee WB (eds). The Ocular Surface, Cornea, Conjunctiva & Tear Film. Elsevier. 2013, Chapter 14. 20. Tims JS, Lee WB. Keratoplasty in Ocular Surface
Mathys KC, Cohen KL. Impact of Nepafenac 0.1% on macular thickness and postoperative visual acuity after cataract surgery in patients at low risk for cystoid macular edema. Eye 2010;24:90-96
Lee WB, Mathys KC. Traumatic Wound Dehiscence after Deep Anterior Lamellar Keratoplasty. J Cataract Refract Surg 2009;35:1129-31
Mathys KC, Garg S. Central Hemiretinal Arterial Occlusion. N Engl J Med 2008;358:2716
Mathys KC, Cohen KL, Bagnell, CR. Identification of unknown intraocular material after cataract surgery: evaluating a potential cause of toxic anterior segment syndrome. Journal of Cataract and Refract Surg 2008;34:465-9
Mathys KC. Sudden, painful vision loss in a young, healthy woman. Eye/Net 2007; Nov/Dec:73-75
Mathys KC, Cohen KL, Armstrong BD. Determining factors for corneal endothelial cell loss by using bimanual microincision phacoemulsification and power modulation. Cornea 2007;26:1049-55
Wigger A, Sánchez MM, Mathys KC, Ebner K, Liu D, Kresse A, Thrivikraman K, Neumann IDN, Plotsky PM, Landgraf R. Alterations in central neuropeptide expression, release, and receptor binding in rats bred for high anxiety: critical role of Vasopressin. Neuropsychopharmacology 2003;29:1-14
Mathys KC, Ponnampalam SN, Padival S, Nagaraj RH. Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Biochemical and Biophysical Research Communications 2002;297:863-869
Communications to Scientific Congress and Lectures
Lee WB, Mathys KC. Pearls to prevent peril in combined descemet’s stripping automated endothelial keratoplasty. VIII Congresso S.I.C.S.S.O. International Scientific Meeting, Venice, Italy (June, 2009)
Mathys KC, Lee WB. Deep anterior lamellar keratoplasty (DALK), how steep is the learning curve? Cornea Society/Eye Bank Association of America Educational Symposium, lecture (Nov. 2008)
Mathys KC, Cohen KL. Effect of nepafenac on macular thickness following uncomplicated cataract surgery. Association for Research in Vision and Ophthalmology annual meeting. Abstract 5674/A589 (May, 2008)
Aschbrenner MW, Mathys KC, Cohen KL. Do biological parameters and phaco metrics affect OCT measured CMT with and without nepafenac 0.1% treatment? Association for Research in Vision and Ophthalmology annual meeting. Abstract 389/A83 (May, 2008)
Mathys KC. Characterization of intraocular debris following injection of AR-40 pcIOLs. North Carolina Society of Eye Physicians and Surgeons annual meeting (Sept. 2007)
Mathys KC. Factors affecting corneal endothelial cell loss using bimanual microincision phacoemulsification and power modulation. Presented at the Arthur C. Chandler Scientific Symposium, University of North Carolina at Chapel Hill (June, 2007)
Mathys K, Cohen KL, Bagnell CR, Baker RK. Characterization of intraocular debris following injection of AR-40 pcIOLs. Association for Research in Vision and Ophthalmology annual meeting. Abstract 619/B540 (May, 2007)
Mathys K, Cohen KL, Armstrong BD. Corneal endothelial cell density before and after bimanual microincision phacoemulsification. Association for Research in Vision and Ophthalmology annual meeting. Abstract 619/B540 (May, 2006)
Mathys KC, Padival S, Nagaraj RH. Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Irwin H. Lepow Student Research Day, CWRU SOM (2002)
Huot RL, Smith LG, Cáceda R, Mathys KC, Insel TR, Plotsky PM, Sánchez MM. Nuerboiological effects of early adverse experience in developing rhesus monkeys. Society for Neuroscience Abstract 2001;27:476.6
Mathys KC, Young LY, Plotsky PM, Insel TR, Sánchez MM. Localization of urocortin in the rhesus monkey CNS and pituitary. Society for Neuroscience Abstract 2000;26:719.8
Plotsky PM, Zurich KJ, Mathys C, Sánchez MM, Thrivikraman KV, Holsboer F, Wigger A, Neuman I, Landgraf R. Region-specific alterations in corticotropin releasing factor (CRF) mRNA distribution and CRF-R2 binding in rats bred for high anxiety-related behavior. Society for Neuroscience Abstract 2000;26:206.7
Sánchez MM, Young LJ, Mathys KC, Plotsky PM, Insel TR. Different rearing conditions affect the development of corticotropin releasing factor (CRF) and vasopressin (AVP) systems in non-human primate systems. Society for Neuroscience Abstract 1999;25:443